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Moisture content by Karl Fischer method

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Moisture content by Karl Fischer method

1. Scope

  • Moisture content by Karl Fischer (USP method 1a) for pharmaceutical substances.

2. Introduction

2.1-What is Karl Fischer method?
  • It is titrimetric determination of water based upon the quantitative reaction of water with an anhydrous solution of sulfur dioxide and iodine in the presence of a buffer that reacts with hydrogen ions.

3. Procedure of measurement

  • ISO17025 certified method.

4. Proposed service price

  • 300 LE X no. of solvents analyzed

5. References

  • United States Pharmacopeia (USP) 43: online version. General Chapter 281. Residue on Ignition

You can also check our other services:

1- Total protein analysis
2- Analysis of vitamins
3- Fixed oils analysis
4- Amino Acid Analysis
5- Analysis of Preservatives
6-  Loss o drying
7- Residue on Ignition (sulfated ash)
8- Total soluble solids (BRIX)
Categories: Formulation & Stability, Tests Tags: Karl fisher, Moisture content, Titrimetric Karl fisher
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  • Description
Description

Moisture content by Karl Fischer method

1. Scope

  • Moisture content by Karl Fischer (USP method 1a) for pharmaceutical substances.

2. Introduction

2.1-What is Karl Fischer method?
  • It is titrimetric determination of water based upon the quantitative reaction of water with an anhydrous solution of sulfur dioxide and iodine in the presence of a buffer that reacts with hydrogen ions.

3. Procedure of measurement

  • ISO17025 certified method.

4. Proposed service price

  • 300 LE X no. of solvents analyzed

5. References

  • United States Pharmacopeia (USP) 43: online version. General Chapter 281. Residue on Ignition

You can also check our other services:

1- Total protein analysis
2- Analysis of vitamins
3- Fixed oils analysis
4- Amino Acid Analysis
5- Analysis of Preservatives
6-  Loss on drying
7- Residue on Ignition (sulfated ash)
8- Total soluble solids (BRIX)

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