Exosomes purification, quantification and characterization

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Exosomes referrers to the cytokines and growth factors secreted by the cells in the form of vesicles ranging from nanovesicles to micro vesicles and often referred to as extracellular vesicles. These vesicles contain proteins, mRNA, growth factors and cytokines that play a major role in cell communication, and in case of stem cell-derived exosomes, they stimulate the healing and repairing powers of the damaged tissues, harnessing the power of stimulating endogenous stem and progenitor cells to proliferate and increase the levels of regeneration giving the main advantage of acellular therapy.

1. Stem cell-derived exosomes:

We offer high-grade purified mesenchymal stem cell-derived exosomes and extracellular vesicles for in vitro studies or in vivo applications.

2. Quantification and characterization of stem cell-derived exosomes:

We offer quantification of the number of exosomes in solutions, frozen and lyophilized samples using nanoparticle quantification, in addition to the specific markers characterization using flow cytometry.

Service price

Price is determined based on the type of service needed.

You can also check our other services:

1- Cytotoxicity assays

2- Cell migration / Wound healing assay

3- Western Blotting

4- Quantitative PCR services (qPCR).

5- Conventional PCR services

6- PCR primer design and validation

Exosomes purification, quantification & characterization

Exosomes are small extracellular vesicles ranging from (30-100) nm in diameter. They are secreted organelles with critical role in signaling between cells. they have the properties of their original mother cell. Exosomes secreted from some cell types, including mesenchymal stem cells, carrying biological factors implicated in the protection, immunomodulation ,regeneration, and angiogenesis of damaged tissues. Due to these properties, exosomes have attracted attention in regenerative therapies. Stem cell derived exosomes also have other applications in many fields as: 1-Diagnostic biomarker: exosomes can be used for the early diagnosis of many diseases as Tuberculosis.2-Regenerative medicine: stem cell derived exosomes have regenerative properties as a new tool in regenerative research, have implications for cardiac and tendon regeneration, wound healing. 3-Drug delivery system: Exosomes are attracting the curiosity of researchers to develop exosome-based drug delivery systems. since exosomes have many properties as: a-High biocompatibility(non immunogenic).b-Tissue specific-Long circulating half life-time.d-high compartmentalization-cargo protection from degradation. we also provide stem cell derived exosome characterization using Transmission electron microscopy images and flowcytometry. we also provide measuring exosomes concentration using BCA & Bradford assay kits

Exosomes purification, quantification and characterization

1. Stem cell-derived exosomes: