HPLC
Cellular Drug Uptake by HPLC
EGP1,250.00 / compoundMeasuring the transport or internalization of biologically active molecules (drugs, nanoparticles,) into cells that are key factors in
- The discovery and development of novel drugs.
- Determination of the compound’s potency and efficacy.
- Limiting the toxic effects and increasing the desired effects.
- Estimating the drug selectivity that often depends on the presence or absence of specific transporters.
You can also check our other services:
1- Cytotoxicity Assays
2- Flow cytometric assays
3- Multipurpose treated-flasks
4- Cell migration / wound healing assay
5- Western Blotting
Determination of phenolics and flavonoids
EGP150.00 – EGP750.00 / sampleFlavonoids and phenolics are among the abundant compounds available in extracts of natural products. We can help you determine the total phenolic and flavonoid content in your sample, and even estimate them qualitatively and quantitatively.
HPLC measurements
High Pressure Liquid Chromatography HPLC is the golden standard device for quantitative analysis for the vast majority of analytes. HPLC allows simultaneous analysis of samples with high resolution, sensitivity and reproducibility.
Liquid Chromatography High Resolution Mass Spectrometry (LC-HR-MS)
EGP0.00 / sampleHPLC-QTOF-HRMS
The application of mass spectrometry (MS) coupled to liquid chromatography (LC) has been recognized as a revolutionary breakthrough in the analysis and characterization of compounds. LC can efficiently separate compounds from a variety of complex samples, and MS, especially multistage (tandem), can be used to detect analytes with superior sensitivity. While DAD and fluorometric detectors can accomplish the same task with good sensitivity, insufficient selectivity and interference from molecules with similar chromatographic behavior remain the major drawback of these techniques.
The applications of LCMS in the area of natural products, as example, is incomparable to other techniques including; preliminary screening and dereplication, quality control and fingerprinting, and metabolism and pharmacokinetics studies.