Entrapment enhancer
Cellular Drug Uptake by Flow cytometry
EGP700.00 – EGP1,000.00 / compound- Cellular uptakeplays an essential role in drug bioactivity, for example, the internalization and accumulation of drugs into cancer cells are crucial for the therapeutic effect against tumors.
- Flow cytometry has the advantage of measuring the fluorescence of individual Cells, accordingly it can measure the cellular uptake, entrapment, and accumulation of any fluorescent drug accurately and quantitatively.
- Flow cytometry can measure all aspects of cellular pharmacokinetics including the intracellular uptake, entrapment, and accumulation of any fluorescent drug accurately and quantitatively.
- with relatively weak fluorescence due to high laser excitation and a high-gain photomultiplier system.
- Non-fluorescent drugs can be evaluated as well after conjugation with a suitable fluorophore.
You can also check our other services:
1- Cytotoxicity Assays
2- Flow cytometric assays
3- Multipurpose treated-flasks
4- Cell migration / wound healing assay
5- Western Blotting
Cellular Drug Uptake by HPLC
EGP1,250.00 / compoundMeasuring the transport or internalization of biologically active molecules (drugs, nanoparticles,) into cells that are key factors in
- The discovery and development of novel drugs.
- Determination of the compound’s potency and efficacy.
- Limiting the toxic effects and increasing the desired effects.
- Estimating the drug selectivity that often depends on the presence or absence of specific transporters.